The BHLHE40 Polyclonal Antibody (CAB6534) is a valuable tool for researchers studying BHLHE40, a transcription factor involved in regulating gene expression. This antibody, produced in rabbits, is highly specific to human samples and is optimized for use in Western blot applications. By binding to the BHLHE40 protein, this antibody allows for the detection and analysis of BHLHE40 in various cell types, making it ideal for studies in molecular biology and developmental biology.
BHLHE40, also known as DEC1, is a key player in the regulation of circadian rhythms, cell differentiation, and apoptosis. Its role in controlling gene expression makes it a target of interest in research on cancer, metabolic disorders, and cardiovascular diseases. Understanding the function of BHLHE40 is essential for uncovering its impact on various biological processes and its potential as a therapeutic target in disease treatment.
Product Name:
BHLHE40 Rabbit Polyclonal Antibody
SKU:
CAB6534
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-300 of human BHLHE40 (NP_003661.1).
This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation.
Purification Method:
Affinity purification
Gene ID:
8553
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using BHLHE40 Rabbit pAb (CAB6534) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
