The BGN Polyclonal Antibody (CAB3137) is a valuable tool for researchers studying the BGN protein, which plays a critical role in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the BGN protein, this antibody allows for the accurate detection and analysis of BGN in different cell types, making it ideal for investigations in fields such as cell biology and tissue engineering.BGN, also known as biglycan, is a small leucine-rich proteoglycan that is involved in extracellular matrix organization and cell signaling.
Its functions in cell adhesion, migration, and differentiation make it a key player in processes such as wound healing, tissue repair, and development. Research on BGN is crucial for understanding its role in various physiological and pathological conditions, including fibrosis, arthritis, and cardiovascular diseases. The BGN Polyclonal Antibody provides researchers with a valuable tool to explore the functions and mechanisms of BGN in health and disease.
Product Name:
BGN Rabbit Polyclonal Antibody
SKU:
CAB3137
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human BGN (NP_001702.1).
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.
Purification Method:
Affinity purification
Gene ID:
633
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BGN Rabbit pAb (CAB3137) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
