BGLAP Rabbit Polyclonal Antibody (CAB18241)
- SKU:
- CAB18241
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | BGLAP Rabbit Polyclonal Antibody |
SKU: | CAB18241 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-95 of human Osteocalcin (BGLAP) (NP_954642.1). |
Sequence: | MRAL TLLA LLAL AALC IAGQ AGAK PSGA ESSK GAAF VSKQ EGSE VVKR PRRY LYQW LGAP VPYP DPLE PRRE VCEL NPDC DELA DHIG FQEA YRR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | OC; BGP; OCN; Osteocalcin (BGLAP) |
Positive Sample: | U-87 MG,Mouse fat |
Cellular Localization: | Secreted. |
Calculated MW: | 11kDa |
Observed MW: | 11kDa |
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Purification Method: | Affinity purification |
Gene ID: | 632 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |