The BGAT Rabbit Monoclonal Antibody (CAB5207) is a cutting-edge tool designed for research involving BGAT, a key enzyme involved in the biosynthesis of a unique class of glycosphingolipids known as globo-series glycosphingolipids. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for a wide range of applications, including Western blotting and immunohistochemistry.BGAT, also known as A4GALT, plays a crucial role in the biosynthesis of globo-series glycosphingolipids, which have been implicated in various biological processes, including cell adhesion, migration, and immune response modulation.
Dysregulation of BGAT function has been associated with several diseases, making it a promising target for research in cancer biology, immunology, and developmental biology.By using the BGAT Rabbit Monoclonal Antibody (CAB5207), researchers can effectively detect and analyze BGAT protein expression in different cell types and tissues, providing valuable insights into the role of BGAT in health and disease. This antibody is a valuable tool for studying glycosphingolipid biosynthesis and its implications in various physiological and pathological conditions.
Product Name:
BGAT Rabbit Monoclonal Antibody
SKU:
CAB5207
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGAT (P16442).
Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
41kDa
Observed MW:
41kDa
This gene encodes proteins related to the first discovered blood group system, ABO. Variation in the ABO gene (chromosome 9q34.2) is the basis of the ABO blood group, thus the presence of an allele determines the blood group in an individual. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
28
Clone Number:
ARC1251
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BGAT Rabbit mAb (CAB5207) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
