The BFAR Polyclonal Antibody (CAB8308) is a vital tool for research involving the BFAR protein, a key player in various cellular processes such as signal transduction, protein binding, and cell adhesion. This antibody, generated in rabbits, exhibits a high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the BFAR protein, researchers can effectively detect and analyze its expression in different cell types, making it ideal for studies in cell biology and cancer research.
BFAR, also known as Bifocal Adhesion Related, is involved in regulating cellular functions such as cell migration, proliferation, and survival. Its role in various cellular processes highlights its importance in understanding disease mechanisms, particularly in cancer progression and metastasis. By studying the function of BFAR, researchers can gain insights into potential therapeutic targets for cancer treatment and the development of novel therapies targeting cell adhesion and motility pathways.
Product Name:
BFAR Rabbit Polyclonal Antibody
SKU:
CAB8308
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human BFAR (NP_057645.1).
Enables caspase binding activity; protein-macromolecule adaptor activity; and ubiquitin protein ligase activity. Involved in negative regulation of IRE1-mediated unfolded protein response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Acts upstream of or within negative regulation of apoptotic process. Located in endoplasmic reticulum and membrane.
Purification Method:
Affinity purification
Gene ID:
51283
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BFAR antibody (CAB8308) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
