The BetaIII Tubulin Polyclonal Antibody (CAB17073) is a valuable tool for researchers studying the role of BetaIII Tubulin, a cytoskeleton protein essential for neuron development and function. This rabbit-derived antibody is highly specific to human BetaIII Tubulin and has been validated for use in Western blot applications. By targeting BetaIII Tubulin, researchers can effectively visualize and analyze the protein in various cell types, making it an ideal choice for neuroscience and cancer research studies.BetaIII Tubulin is a crucial component of microtubules in neurons, playing a key role in neuronal migration and axon guidance.
Dysregulation of BetaIII Tubulin has been implicated in various neurological disorders, making it a promising therapeutic target for conditions such as Alzheimer's disease, Parkinson's disease, and brain tumors. The BetaIII Tubulin Polyclonal Antibody is a valuable tool for unraveling the complexities of BetaIII Tubulin biology and developing targeted therapies for neurological diseases.
Product Name:
βIII-Tubulin Rabbit Polyclonal Antibody
SKU:
CAB17073
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human βIII-Tubulin/β3-Tubulin (NP_006077.2).
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
10381
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using βIII-Tubulin Rabbit pAb (CAB17073) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
