The Beta-Sarcoglycan Polyclonal Antibody (CAB6979) is a versatile tool for researchers studying beta-sarcoglycan, a key component of the sarcoglycan complex that plays a critical role in maintaining muscle cell membrane integrity. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it an ideal choice for Western blot applications.Beta-sarcoglycan is involved in various muscle-related diseases, including muscular dystrophies, making it an important target for investigation in the field of muscle biology and disease research.
By utilizing the Beta-Sarcoglycan Polyclonal Antibody, researchers can accurately detect and analyze beta-sarcoglycan expression in different cell types, providing valuable insights into its function and potential implications in muscle-related disorders.With its high specificity and reliability, the Beta-Sarcoglycan Polyclonal Antibody (CAB6979) is a valuable tool for scientists and researchers looking to deepen their understanding of beta-sarcoglycan and its role in muscle cell biology and disease pathology.
Product Name:
SGCB Rabbit Polyclonal Antibody
SKU:
CAB6979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1).
Cell membrane, Cytoplasm, Single-pass type II membrane protein, cytoskeleton, sarcolemma.
Calculated MW:
35kDa
Observed MW:
45kDa
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Purification Method:
Affinity purification
Gene ID:
6443
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SGCB antibody (CAB6979) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
