The Beta-Defensin 132 Polyclonal Antibody (CAB1074) is a versatile tool for researchers studying the immune system and antimicrobial defense mechanisms. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in various immunology and microbiology studies.Beta-defensins are a family of antimicrobial peptides that play a crucial role in the body's defense against pathogens. Beta-Defensin 132, in particular, has been identified as an important component of the innate immune response, with implications for host defense and inflammation regulation.
With its ability to specifically target and detect Beta-Defensin 132 in various cell types, this polyclonal antibody is essential for studying the role of this antimicrobial peptide in conditions such as infectious diseases, inflammatory disorders, and cancer. By understanding the mechanisms by which Beta-Defensin 132 contributes to immune defense, researchers can pave the way for the development of novel therapies targeting antimicrobial resistance and immune dysregulation.
Product Name:
DEFB132 Rabbit Polyclonal Antibody
SKU:
CAB1074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132 (NP_997352.1).
Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.
Purification Method:
Affinity purification
Gene ID:
400830
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DEFB132 antibody (CAB1074) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
