The BDNF Rabbit Monoclonal Antibody (CAB4873) is a powerful tool for researchers studying Brain-Derived Neurotrophic Factor (BDNF), a key molecule involved in the growth, development, and maintenance of neurons in the brain. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting BDNF in various samples, particularly in Western blot applications.BDNF plays a crucial role in neuronal survival, differentiation, and synaptic plasticity, making it a valuable target for research in neurobiology, neurodevelopmental disorders, and neurodegenerative diseases.
By targeting BDNF with this antibody, researchers can investigate the function and regulation of this important neurotrophic factor in both normal and pathological conditions.The BDNF Rabbit Monoclonal Antibody (CAB4873) offers researchers a reliable tool for studying the complex role of BDNF in the brain, providing valuable insights into neurodevelopment, cognition, and disease pathology. Its high specificity and sensitivity make it a valuable asset for studies exploring the therapeutic potential of targeting BDNF in various neurological disorders.
Product Name:
BDNF Rabbit Monoclonal Antibody
SKU:
CAB4873
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human BDNF (P23560).
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Purification Method:
Affinity purification
Gene ID:
627
Clone Number:
ARC0303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Confocal imaging of paraffin-embedded Rat brain using BDNF Rabbit mAb (A4873,dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007,dilution 1:500)(Red).DAPI was used for nuclear staining (Blue). Objective: 40x. Perform microwave antigen retrieval with 0.01 M citRate buffer (pH 6.0) prior to IF staining.
