The BDNF Polyclonal Antibody (CAB11028) is a valuable tool for researchers studying brain-derived neurotrophic factor (BDNF), a key protein involved in the growth, development, and maintenance of neurons. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.BDNF plays a crucial role in synaptic plasticity, neuronal survival, and cognitive function, making it a key target for research in neurobiology, neurodegenerative diseases, and psychiatric disorders.
The BDNF Polyclonal Antibody enables detection and analysis of BDNF protein expression in various cell types, providing researchers with valuable insights into its functions and potential therapeutic applications.By understanding the signaling pathways and mechanisms of action of BDNF, researchers can uncover new insights into brain development, neuroplasticity, and cognitive function. The BDNF Polyclonal Antibody is a powerful tool for advancing research in this important area of neuroscience.
Product Name:
BDNF Rabbit Polyclonal Antibody
SKU:
CAB11028
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 129-247 of human BDNF (NP_733931.1).
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Purification Method:
Affinity purification
Gene ID:
627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of U-251MG cells, using BDNF antibody (CAB11028) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
