Bdnf Antibody (PACO33724)
- SKU:
- PACO33724
- Product Type:
- Antibody
- Reactivity:
- Rat
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Bdnf Antibody (PACO33724)
The BDNF Polyclonal Antibody (PACO33724) is a valuable tool for researchers studying brain-derived neurotrophic factor (BDNF), a key protein involved in neuronal development, function, and plasticity. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.BDNF is essential for promoting the growth, survival, and differentiation of neurons in the central nervous system, making it a crucial factor in neurogenesis and synaptic plasticity. Dysregulation of BDNF signaling has been implicated in various neurological disorders, such as Alzheimer's disease, depression, and epilepsy, highlighting the importance of studying this protein in both health and disease states.
By targeting the BDNF protein, researchers can gain insights into its role in neural development and function, as well as potential therapeutic strategies for neurological conditions. The BDNF Polyclonal Antibody (PACO33724) offers a reliable tool for detecting and analyzing BDNF expression in different cell types, facilitating research in neuroscience and drug development efforts aimed at harnessing the therapeutic potential of BDNF modulation.
| Antibody Name: | Bdnf Antibody (PACO33724) |
| Antibody SKU: | PACO33724 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat, Human |
| Immunogen: | Recombinant Rat Brain-derived neurotrophic factor protein (137-237AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Bdnf antibody at 2µg/ml + U251 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 29 kDa Observed band size: 29 kDa . |
| Background: | During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS |
| Synonyms: | Brain-derived neurotrophic factor (BDNF), Bdnf |
| UniProt Protein Function: | During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
| NCBI Summary: | plays a role in the development of hippocampal long term potentiation; involved in regulation of synaptic plasticity [RGD, Feb 2006] |
| UniProt Code: | P23363 |
| NCBI GenInfo Identifier: | 114904 |
| NCBI Gene ID: | 24225 |
| NCBI Accession: | P23363.1 |
| UniProt Secondary Accession: | P23363,Q53YL8, |
| UniProt Related Accession: | P23363 |
| Molecular Weight: | 28,109 Da |
| NCBI Full Name: | Brain-derived neurotrophic factor |
| NCBI Synonym Full Names: | brain-derived neurotrophic factor |
| NCBI Official Symbol: | Bdnf  |
| NCBI Protein Information: | brain-derived neurotrophic factor; brain derived neurotrophic factor; brain derived neurothrophic factor |
| UniProt Protein Name: | Brain-derived neurotrophic factor |
| Protein Family: | BDNF/NT-3 growth factors receptor |
| UniProt Gene Name: | Bdnf  |
| UniProt Entry Name: | BDNF_RAT |
| ELISA Kits |
| Rat BDNF ELISA Kit |
| Rat BDNF (Brain Derived Neurotrophic Factor) CLIA Kit (RTES00618) |
| Rat Brain-derived neurotrophic factor (Bdnf) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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