BDKRB1 Rabbit Polyclonal Antibody (CAB1959)
- SKU:
- CAB1959
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BDKRB1 Rabbit Polyclonal Antibody |
SKU: | CAB1959 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BDKRB1 (NP_000701.2). |
Sequence: | MASS WPPL ELQS SNQS QLFP QNAT ACDN APEA WDLL HRVL PTFI ISIC FFGL LGNL FVLL VFLL PRRQ LNVA EIYL ANLA ASDL VFVL GLPF WAEN IWNQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | B1R; BKR1; B1BKR; BKB1R; BRADYB1; BDKRB1 |
Positive Sample: | A-549,A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Purification Method: | Affinity purification |
Gene ID: | 623 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |