The BDKRB1 Polyclonal Antibody (CAB1959) is a valuable tool for researchers studying the BDKRB1 protein, a member of the bradykinin receptor family involved in various physiological processes, including inflammation, pain sensation, and blood pressure regulation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.BDKRB1 is known to be expressed in various tissues, including the cardiovascular system, lungs, and central nervous system, making it a target of interest in cardiovascular diseases, respiratory conditions, and neurological disorders.
By binding to the BDKRB1 protein, this antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights into its role in health and disease.Understanding the function of BDKRB1 is essential for developing therapeutic strategies targeting this receptor for the treatment of conditions related to inflammation, pain, and blood pressure regulation. With its high reactivity and specificity, the BDKRB1 Polyclonal Antibody (CAB1959) is a reliable tool for researchers seeking to explore the potential of BDKRB1 as a therapeutic target in various disease contexts.
Product Name:
BDKRB1 Rabbit Polyclonal Antibody
SKU:
CAB1959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BDKRB1 (NP_000701.2).
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Purification Method:
Affinity purification
Gene ID:
623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BDKRB1 Rabbit pAb (CAB1959) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
