The BDH2 Polyclonal Antibody (PAC041254) is a high-quality research tool designed for studying the BDH2 protein, an enzyme involved in lipid metabolism. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is optimized for Western blot applications. By binding specifically to the BDH2 protein, it allows for accurate detection and analysis in a variety of cell types, making it a valuable tool for research in biochemistry and metabolism.BDH2, also known as 3-hydroxybutyrate dehydrogenase, plays a crucial role in the metabolism of ketone bodies and fatty acids.
Its involvement in lipid metabolism makes it a key target for studying metabolic disorders, obesity, and diabetes. By understanding the function and regulation of BDH2, researchers can uncover potential therapeutic targets for treating metabolic diseases and developing personalized medicine approaches.Overall, the BDH2 Polyclonal Antibody is a reliable choice for researchers studying lipid metabolism and related disorders. Its specificity and sensitivity make it a valuable tool for advancing our understanding of BDH2 function in health and disease.
Antibody Name:
BDH2 Antibody (PACO41254)
Antibody SKU:
PACO41254
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human 3-hydroxybutyrate dehydrogenase type 2 protein (1-245AA)
Immunohistochemistry of paraffin-embedded human liver tissue using PACO41254 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO41254 at dilution of 1:100.
Background:
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid, (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity).
Synonyms:
3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (Dehydrogenase/reductase SDR family member 6) (Oxidoreductase UCPA) (R-beta-hydroxybutyrate dehydrogenase) (Short chain dehydrogenase/reductase family 15C member 1), BDH2, DHRS6 SDR15C1
UniProt Protein Function:
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase ().
DHRS6; EFA6R; SDR15C1; UCPA-OR; UNQ6308; PRO20933Â Â
NCBI Protein Information:
3-hydroxybutyrate dehydrogenase type 2
UniProt Protein Name:
3-hydroxybutyrate dehydrogenase type 2
UniProt Synonym Protein Names:
Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1