BCS1L Rabbit Polyclonal Antibody (CAB7647)
- SKU:
- CAB7647
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BCS1L Rabbit Polyclonal Antibody |
SKU: | CAB7647 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-240 of human BCS1L (NP_004319.1). |
Sequence: | RKGV QLGL VAFR RHYM ITLE VPAR DRSY AWLL SWLT RHST RTQH LSVE TSYL QHES GRIS TKFE FVPS PGNH FIWY RGKW IRVE RSRE MQMI DLQT GTPW ESVT FTAL GTDR KVFF NILE EARE LALQ QEEG KTVM YTAV GSEW RPFG YPRR RRPL NSVV LQQG LADR IVRD VQEF IDNP KWYT DRGI PYRR GYLL YGPP GCGK SSFI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | BCS; BJS; PTD; BCS1; FLNMS; h-BCS; MC3DN1; h-BCS1; GRACILE; Hs.6719; BCS1L |
Positive Sample: | HepG2,SKOV3,MCF7,HeLa,Mouse heart,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Single-pass membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 617 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |