The BCMO1 Polyclonal Antibody (CAB15848) is a valuable tool for researchers studying the BCMO1 protein, which plays a crucial role in Vitamin A metabolism. This antibody, generated in rabbits, displays high specificity for human samples and has been validated for use in Western blot applications. By targeting the BCMO1 protein, this antibody enables the accurate detection and analysis of BCMO1 levels in various cell types, making it ideal for investigations in the fields of nutrition, metabolism, and diseases related to Vitamin A deficiency.
BCMO1, also known as beta-carotene 15,15'-monooxygenase 1, is a key enzyme involved in the conversion of dietary beta-carotene into Vitamin A, a process essential for maintaining vision, immune function, and skin health. Dysregulation of BCMO1 activity has been linked to conditions like night blindness, xerophthalmia, and impaired immune responses. Research on BCMO1 is crucial for understanding how Vitamin A is metabolized and utilized in the body, and may lead to the development of novel therapies for Vitamin A-related disorders.
Product Name:
BCMO1 Rabbit Polyclonal Antibody
SKU:
CAB15848
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2).
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
Purification Method:
Affinity purification
Gene ID:
53630
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BCMO1 Rabbit pAb (CAB15848) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
