The BCLAF1 Polyclonal Antibody (CAB16473) is a valuable tool for researchers studying the BCLAF1 protein, which plays a critical role in various cellular processes, including apoptosis, DNA damage response, and RNA metabolism. This antibody, produced in rabbits, exhibits a high level of reactivity with human samples and is validated for use in Western blot applications.BCLAF1, also known as Bcl-2-associated transcription factor 1, is involved in the regulation of gene expression and cell survival, making it a key player in cancer biology and other disease processes.
By targeting the BCLAF1 protein, researchers can gain valuable insights into its function and its potential as a therapeutic target in cancer and other diseases.With its ability to specifically bind to the BCLAF1 protein, this polyclonal antibody enables the detection and analysis of BCLAF1 in various cell types and tissues, making it an essential tool for studies in molecular biology, cancer research, and beyond. Researchers can leverage the power of this antibody to further our understanding of BCLAF1 and its implications in health and disease.
Product Name:
BCLAF1 Rabbit Polyclonal Antibody
SKU:
CAB16473
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 330-552 of human BCLAF1 (NP_001070909.1).
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9774
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of SH-SY5Y cells, using BCLAF1 antibody (CAB16473) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
