The BCL9 Polyclonal Antibody is a valuable tool for researchers studying the BCL9 protein, a key regulator of the Wnt signaling pathway. This antibody is produced in rabbits and is highly specific to human samples, making it an ideal choice for Western blot applications. By targeting the BCL9 protein, this antibody allows for the detection and analysis of Wnt signaling pathways in various cell types.The Wnt signaling pathway plays a critical role in cell proliferation, differentiation, and migration, making it a key player in development, tissue regeneration, and disease progression. Dysregulation of this pathway is often associated with various cancers and other diseases.
By using the BCL9 Polyclonal Antibody in their research, scientists can gain insights into the role of BCL9 in Wnt signaling and its implications for disease development and progression.Whether studying cancer biology, developmental biology, or regenerative medicine, researchers can benefit from the specificity and sensitivity of the BCL9 Polyclonal Antibody in their experiments. Its ability to selectively target the BCL9 protein makes it a valuable tool for investigating the complex mechanisms underlying Wnt signaling and its involvement in various physiological and pathological processes.
Product Name:
Bcl9 Polyclonal Antibody
SKU:
CAB22868
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant protein of human Bcl9.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
LGS; Bcl9
Positive Sample:
Mouse brain
Cellular Localization:
Nucleus.
Calculated MW:
149kDa
Observed MW:
149kDa
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
Purification Method:
Affinity purification
Gene ID:
607
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using Bcl9 Rabbit pAb (CAB22868) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
