Bcl-W Rabbit Polyclonal Antibody (CAB1158)
- SKU:
- CAB1158
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Bcl-W Rabbit Polyclonal Antibody |
SKU: | CAB1158 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-193 of human Bcl-W (NP_004041.2). |
Sequence: | MATP ASAP DTRA LVAD FVGY KLRQ KGYV CGAG PGEG PAAD PLHQ AMRA AGDE FETR FRRT FSDL AAQL HVTP GSAQ QRFT QVSD ELFQ GGPN WGRL VAFF VFGA ALCA ESVN KEME PLVG QVQE WMVA YLET QLAD WIHS SGGW AEFT ALYG DGAL EEAR RLRE GNWA SVRT VLTG AVAL GALV TVGA FFAS K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | BCLW; BCL-W; PPP1R51; BCL2-L-2; Bcl-W |
Positive Sample: | Mouse brain,Rat brain,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane, Peripheral membrane protein. |
Calculated MW: | 21kDa |
Observed MW: | 18kDa |
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
Purification Method: | Affinity purification |
Gene ID: | 599 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |