The BCL2L14 Polyclonal Antibody (CAB6478) is a valuable tool for researchers studying the BCL2L14 protein, which belongs to the Bcl-2 family of proteins involved in regulating cell death. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BCL2L14 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it ideal for studies in apoptosis and cancer research.
BCL2L14, also known as Bcl-G, has been implicated in promoting cell survival and inhibiting apoptosis in certain contexts. Understanding its role in regulating cell death is crucial for advancing our knowledge of cancer biology and potential therapeutic strategies. By targeting BCL2L14, researchers aim to uncover new insights into how this protein influences cell fate and potentially identify novel approaches for cancer treatment.
Product Name:
BCL2L14/BCLG Rabbit Polyclonal Antibody
SKU:
CAB6478
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human BCL2L14/BCLG (NP_620049.1).
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.
Purification Method:
Affinity purification
Gene ID:
79370
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BCL2L14/BCLG antibody (CAB6478) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
