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BCL2L12 Rabbit Monoclonal Antibody (CAB19808)

SKU:
CAB19808
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:BCL2L12 Rabbit Monoclonal Antibody
SKU:CAB19808
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human BCL2L12 (Q9HB09).
Sequence:GPPS TEKE AILR RLVA LLEE EAEV INQK LASD PALR SKLV RLSS DSFA RLVE LFCS RDDS SRPS RACP GPPP PSPE PLAR LALA MELS RRVA GLGG TLAG L
Tested Applications:WB IHC-P IP ELISA
Recommended Dilution:WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsIHC-P,1:50 - 1:200
Positive Sample:MCF7,PC-3
Conjugate:Unconjugated
Cellular Localization:Nucleus
Calculated MW:37kDa
Observed MW:32kDa

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:83596
Clone Number:ARC2334
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using BCL2L12 Rabbit mAb (CAB19808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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