Bcl-2 Rabbit Monoclonal Antibody (CAB19693)
- SKU:
- CAB19693
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Bcl-2 Rabbit Monoclonal Antibody |
SKU: | CAB19693 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human Bcl-2 (P10415). |
Sequence: | MAHA GRTG YDNR EIVM KYIH YKLS QRGY EWDA GDVG AAPP GAAP APGI FSSQ PGHT PHPA ASRD PVAR TSPL QTPA APGA AAGP ALSP VPPV VHLT LRQA GDDF SRRY RRDF AEMS SQLH LTPF TARG RFAT VVEE LFRD GVNW GRIV AFFE FGGV MCVE SVNR EMSP LVDN IALW MTEY LNRH LHTW IQDN GGWD AFVE LYGP SMRP LFD |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | Bcl-2; PPP1R50 |
Positive Sample: | 293T,Mouse testis,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein. |
Calculated MW: | 26kDa |
Observed MW: | 26kDa |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 596 |
Clone Number: | ARC0173 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |