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BCL2 Monoclonal Antibody [PAT1B5AT] (CPAB0436)

SKU:
CPAB0436
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1B5AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

BCL2 Monoclonal Antibody [PAT1B5AT] (CPAB0436)

The BCL2 Polyclonal Antibody (CPAB0436) is a high-quality antibody designed for research involving the B-cell lymphoma 2 (BCL2) protein, a key regulator of apoptosis and cell survival. This antibody is produced in rabbits and has been validated for use in Western blot applications. It specifically binds to the BCL2 protein, allowing for accurate detection and analysis in a variety of cell types.BCL2 is a critical protein in the regulation of programmed cell death, or apoptosis, making it a significant target for research in oncology and drug development. Dysregulation of BCL2 is associated with a wide range of diseases, including various types of cancer, making this antibody a valuable tool for studies in cancer biology and therapy development.

With its high reactivity with human samples and proven reliability in Western blotting, the BCL2 Polyclonal Antibody (CPAB0436) is an ideal choice for researchers looking to investigate the role of BCL2 in cell survival, apoptosis, and cancer progression. Its specificity and sensitivity make it a valuable asset for studies aiming to understand the mechanisms of cell death and survival in both normal and disease states.

Product Name:BCL2 Antibody
Product Sku:CPAB0436
Size:5μg
Host Species:Mouse
Immunogen:Anti-human BCL2 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BCL2amino acids 1-211 purified from Ecoli.
Clone:PAT1B5AT.
Reactivity:Other bodies
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:BCL2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Synonyms:Apoptosis regulator Bcl-2, BCL2, B-cell CLL/lymphoma 2, Bcl-2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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