The BCL-2 Rabbit Monoclonal Antibody (CAB19693) is a cutting-edge tool for researchers studying the BCL-2 protein, a key regulator of cell survival and apoptosis. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting BCL-2 in human samples. It has been validated for use in Western blot applications, enabling precise analysis of BCL-2 expression levels in various cellular contexts.BCL-2 is a pivotal player in the apoptotic pathway, promoting cell survival by preventing the activation of pro-apoptotic factors. Dysregulation of BCL-2 has been implicated in a variety of diseases, including cancer and neurodegenerative disorders.
Researchers investigating the molecular mechanisms underlying these conditions will find the BCL-2 Rabbit Monoclonal Antibody to be a valuable asset in their experimental repertoire.By utilizing this antibody, scientists can gain valuable insights into the role of BCL-2 in cellular processes and disease pathogenesis. Its high affinity for the target antigen ensures reliable and reproducible results, making it an essential tool for advancing our understanding of BCL-2 biology and exploring potential therapeutic interventions targeting this protein.
Product Name:
Bcl-2 Rabbit Monoclonal Antibody
SKU:
CAB19693
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human Bcl-2 (P10415).
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
596
Clone Number:
ARC0173
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Bcl-2 Rabbit mAb (CAB19693) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
