Bcl-2 Polyclonal Antibody (CAB16775)
- SKU:
- CAB16775
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
Product Name: | Bcl-2 Polyclonal Antibody |
SKU: | CAB16775 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bcl-2 (NP_000624.2). |
Sequence: | MAHA GRTG YDNR EIVM KYIH YKLS QRGY EWDA GDVG AAPP GAAP APGI FSSQ PGHT PHPA ASRD PVAR TSPL QTPA APGA AAGP ALSP VPPV VHLT LRQA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | Bcl-2; PPP1R50 |
Positive Sample: | Mouse lung |
Cellular Localization: | Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein. |
Calculated MW: | 26kDa |
Observed MW: | 26kDa |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 596 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |