BCDIN3D Rabbit Polyclonal Antibody (CAB17830)
- SKU:
- CAB17830
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BCDIN3D Rabbit Polyclonal Antibody |
SKU: | CAB17830 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human BCDIN3D (NP_859059.1). |
Sequence: | MAVP TELD GGSV KETA AEEE SRVL APGA APFG NFPH YSRF HPPE QRLR LLPP ELLR QLFP ESPE NGPI LGLD VGCN SGDL SVAL YKHF LSLP DGET CSDA SREF RLLC CDID PVLV KRAE KECP FPDA LTFI TLDF MNQR TRKV LLSS FLSQ FGRS VFDI GFCM SITM WIHL NHGD HGLW EFLA HLSS LCHY LLVE PQPW KCYR AAAR RLRK LGLH DFDH FHSL AIRG DMPN QIVQ ILTQ DHGM ELIC CFGN TSWD RSLL LFRA KQTI ETHP IPES LIEK GKEK NRLS FQKQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BCDIN3D |
Positive Sample: | A-431,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm |
Calculated MW: | 33kDa |
Observed MW: | 36kDa |
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs.
Purification Method: | Affinity purification |
Gene ID: | 144233 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |