The CD300A Polyclonal Antibody (CAB10006) is a valuable tool for researchers looking to study the role of CD300A in immune regulation and its potential implications in various diseases. With its high reactivity and specificity for human samples, this antibody is a reliable option for Western blot applications and enables detailed analysis of CD300A expression in different cell types.
By providing insights into the mechanisms underlying immune response modulation, this antibody may contribute to the development of targeted therapies for conditions such as cancer, autoimmune disorders, and chronic inflammation.
Product Name:
BCDIN3D Rabbit Polyclonal Antibody
SKU:
CAB17830
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human BCDIN3D (NP_859059.1).
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs.
Purification Method:
Affinity purification
Gene ID:
144233
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BCDIN3D Rabbit pAb (CAB17830) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
