The BCAT2 Polyclonal Antibody (CAB7426) is designed for research involving BCAT2, a crucial enzyme in the branched-chain amino acid (BCAA) metabolism pathway. This antibody, raised in rabbits, is highly specific for human BCAT2 samples and is validated for use in Western blot applications. It binds specifically to the BCAT2 protein, allowing for accurate detection and analysis in a variety of cell types, making it an ideal tool for studies in metabolism, nutrition, and disease research.BCAT2 plays a critical role in regulating BCAA levels and metabolism, which are essential for protein synthesis, energy production, and overall metabolic function in the body.
Dysregulation of BCAT2 activity has been linked to various metabolic disorders, cancer progression, and neurological diseases, highlighting the importance of studying its role in these contexts. By understanding the function of BCAT2, researchers can uncover potential therapeutic targets for treating metabolic disorders and improving overall health outcomes.
Product Name:
BCAT2 Rabbit Polyclonal Antibody
SKU:
CAB7426
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-392 of human BCAT2 (NP_001181.2).
This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
587
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using BCAT2 Rabbit pAb (CAB7426) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
