The BCAS4 Monoclonal Antibody (PAC02396) is a vital tool for researchers studying BCAS4, a protein involved in various cellular processes such as cell growth and migration. This antibody, produced in mouse, exhibits high specificity and sensitivity when detecting BCAS4 in human samples, making it suitable for applications such as Western blot and immunohistochemistry.BCAS4, also known as Breast Carcinoma Amplified Sequence 4, is implicated in cancer progression and metastasis, making it a promising target for cancer research. By targeting BCAS4, researchers can gain insights into the mechanisms underlying tumor development and potentially identify new therapeutic strategies for cancer treatment.
The utility of the BCAS4 Monoclonal Antibody extends beyond cancer research, as BCAS4 has also been linked to other physiological processes such as cell proliferation and differentiation. By utilizing this antibody, researchers can further explore the functions of BCAS4 in various cellular contexts, ultimately advancing our understanding of its role in health and disease.
Synthesized peptide derived from internal of human BCAS4.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using BCAS4 antibody.
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using BCAS4 antibody.
Background:
A chromosomal aberration involving BCAS4 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS3. Belongs to the cappuccino family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Synonyms:
Breast carcinoma-amplified sequence 4; BCAS4;
UniProt Protein Function:
BCAS4: A chromosomal aberration involving BCAS4 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS3. Belongs to the cappuccino family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: OncoproteinChromosomal Location of Human Ortholog: 20q13.13Biological Process: intracellular transport
