CD239/BCAM Rabbit Polyclonal Antibody (CAB14747)
- SKU:
- CAB14747
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD239/BCAM Rabbit Polyclonal Antibody |
SKU: | CAB14747 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human CD239/CD239/BCAM (NP_005572.2). |
Sequence: | KTLE LRVA YLDP LELS EGKV LSLP LNSS AVVN CSVH GLPT PALR WTKD STPL GDGP MLSL SSIT FDSN GTYV CEAS LPTV PVLS RTQN FTLL VQGS PELK TAEI EPKA DGSW REGD EVTL ICSA RGHP DPKL SWSQ LGGS PAEP IPGR QGWV SSSL TLKV TSAL SRDG ISCE ASNP HGNK RHVF HFGT VSPQ TSQA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AU; LU; CD239; MSK19; CD239/BCAM |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 67kDa |
Observed MW: | 90kDa |
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4059 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |