BBS2 Rabbit Polyclonal Antibody (CAB7425)
- SKU:
- CAB7425
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | BBS2 Rabbit Polyclonal Antibody |
SKU: | CAB7425 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human BBS2 (NP_114091.3). |
Sequence: | MLLP VFTL KLRH KISP RMVA IGRY DGTH PCLA AATQ TGKV FIHN PHTR NQHV SASR VFQS PLES DVSL LNIN QAVS CLTA GVLN PELG YDAL LVGT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BBS; RP74; BBS2 |
Positive Sample: | Mouse testis,Mouse liver,Mouse kidney,Rat liver,Rat brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, centriolar satellite, centrosome, cilium membrane, cytoskeleton, microtubule organizing center. |
Calculated MW: | 80kDa |
Observed MW: | 100kDa |
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.
Purification Method: | Affinity purification |
Gene ID: | 583 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |