The BBOX1 Polyclonal Antibody (CAB5810) is a valuable tool for researchers studying BBOX1, a key enzyme involved in the biosynthesis of carnitine. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the BBOX1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in metabolism and energy production.BBOX1 is essential for the synthesis of carnitine, a molecule critical for the transport of fatty acids into the mitochondria for energy production. Dysregulation of BBOX1 has been linked to various metabolic disorders, making it a potential target for therapeutic interventions.
Research into the role of BBOX1 can provide valuable insights into metabolic processes and may lead to the development of novel treatments for metabolic diseases.In conclusion, the BBOX1 Polyclonal Antibody is a versatile tool for researchers investigating the role of BBOX1 in metabolism and energy production. Its high specificity and reactivity make it an ideal choice for Western blot applications, enabling precise detection and analysis of BBOX1 in various cellular contexts. By advancing our understanding of BBOX1 function, this antibody contributes to the development of new strategies for treating metabolic disorders and improving human health.
Product Name:
BBOX1 Rabbit Polyclonal Antibody
SKU:
CAB5810
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BBOX1 (NP_003977.1).
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
Purification Method:
Affinity purification
Gene ID:
8424
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BBOX1 antibody (CAB5810) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
