Bak Rabbit Monoclonal Antibody (CAB10754)
- SKU:
- CAB10754
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Bak Rabbit Monoclonal Antibody |
SKU: | CAB10754 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-82 of human Bak (NP_001179.1). |
Sequence: | RQEC GEPA LPSA SEEQ VAQD TEEV FRSY VFYR HQQE QEAE GVAA PADP EMVT LPLQ PSST MGQV GRQL AIIG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | BAK; CDN1; BCL2L7; BAK-LIKE; Bak |
Positive Sample: | HeLa,THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane, Single-pass membrane protein. |
Calculated MW: | 23kDa |
Observed MW: | 25kDa |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Purification Method: | Affinity purification |
Gene ID: | 578 |
Clone Number: | ARC0014 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |