The Baiap2l2 Polyclonal Antibody (PACO22209) is a vital tool for researchers studying the Baiap2l2 protein, a key player in regulating cellular functions. This antibody, produced in rabbits, demonstrates high specificity and sensitivity when detecting Baiap2l2 in human samples, making it an ideal choice for Western blot applications. By binding to the Baiap2l2 protein, this antibody enables accurate detection and analysis across various cell types, making it essential for studies in cell biology and molecular mechanisms.
Baiap2l2, also known as BAI1-associated protein 2-like 2, is involved in multiple cellular processes, including cell migration, adhesion, and signaling pathways. Its intricacy in cellular functions makes it a promising target for research on diseases such as cancer, neurological disorders, and immune-related conditions. Understanding the role of Baiap2l2 is crucial for unraveling its potential therapeutic implications in these disease contexts, paving the way for novel treatment strategies.
Antibody Name:
BAIAP2L2 Antibody (PACO22209)
Antibody SKU:
PACO22209
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human BAIAP2L2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from RAW264.7 cells, using BAIAP2L2 antibody.
Background:
Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide By similarity.
BAIAP2L2: Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 22q13.1Cellular Component: actin cytoskeleton; cytosol; vesicle membraneMolecular Function: cytoskeletal adaptor activity; phospholipid bindingBiological Process: actin crosslink formation; actin filament bundle formation; insulin receptor signaling pathway; positive regulation of actin filament polymerization
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. [provided by RefSeq, Dec 2012]
