BAIAP2L1 Rabbit Polyclonal Antibody (CAB8238)
- SKU:
- CAB8238
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
Product Name: | BAIAP2L1 Rabbit Polyclonal Antibody |
SKU: | CAB8238 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 198-388 of human BAIAP2L1 (NP_061330.2). |
Sequence: | DKHC GFAN HIHY YHLQ SAEL LNSK LPRW QETC VDAI KVPE KIMN MIEE IKTP ASTP VSGT PQAS PMIE RSNV VRKD YDTL SKCS PKMP PAPS GRAY TSPL IDMF NNPA TAAP NSQR VNNS TGTS EDPS LQRS VSVA TGLN MMKK QKVK TIFP HTAG SNKT LLSF AQGD VITL LIPE EKDG WLYG EHDV SKA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IRTKS; BAIAP2L1 |
Positive Sample: | HepG2,HeLa,293T,A-549,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytoskeleton. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
Purification Method: | Affinity purification |
Gene ID: | 55971 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |