BAIAP2 Rabbit Polyclonal Antibody (CAB5337)
- SKU:
- CAB5337
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | BAIAP2 Rabbit Polyclonal Antibody |
SKU: | CAB5337 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2 (NP_059344.1). |
Sequence: | PRSS SMAA GLER NGRM RVKA IFSH AAGD NSTL LSFK EGDL ITLL VPEA RDGW HYGE SEKT KMRG WFPF SYTR VLDS DGSD RLHM SLQQ GKSS STGN LLDK DDLA IPPP DYGA ASRA FPAQ TASG FKQR PYSV AVPA FSQG LDDY GARS MSSG SGTL VSTV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | BAP2; WAML; FLAF3; IRSP53; BAIAP2 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Membrane, Peripheral membrane protein, cytoskeleton, filopodium, ruffle. |
Calculated MW: | 61kDa |
Observed MW: | 53kDa/58kDa |
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10458 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |