The BAIAp2 Polyclonal Antibody (CAB5337) is a valuable tool for researchers studying the BAIAp2 protein, which is involved in cellular processes related to immune regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BAIAp2 protein, researchers can accurately detect and analyze this important molecule in various cell types.BAIAp2, also known as an immune regulatory protein, plays a crucial role in modulating immune responses and maintaining immune homeostasis.
Its involvement in immune regulation makes it a key target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of BAIAp2 is essential for developing therapeutic strategies that target or manipulate the immune system in these disease contexts.Overall, the BAIAp2 Polyclonal Antibody (CAB5337) is a reliable tool for researchers investigating the role of BAIAp2 in immune function and its potential implications in disease progression and treatment.
Product Name:
BAIAP2 Rabbit Polyclonal Antibody
SKU:
CAB5337
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2 (NP_059344.1).
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
10458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BAIAP2 antibody (CAB5337) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
