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BAG5 Rabbit Polyclonal Antibody (CAB5794)

SKU:
CAB5794
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 9 Anti-BAG5 Antibody CAB5794
  • Cell Biology Antibodies 9 Anti-BAG5 Antibody CAB5794
  • Cell Biology Antibodies 9 Anti-BAG5 Antibody CAB5794
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:BAG5 Rabbit Polyclonal Antibody
SKU:CAB5794
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 198-447 of human BAG5 (NP_004864.1).
Sequence:GVLI ALLM GVNN NETC RHLS CVLS GLIA DLDA LDVC GRTE IRNY RREV VEDI NKLL KYLD LEEE ADTT KAFD LRQN HSIL KIEK VLKR MREI KNEL LQAQ NPSE LYLS SKTE LQGL IGQL DEVS LEKN PCIR EARR RAVI EVQT LITY IDLK EALE KRKL FACE EHPS HKAV WNVL GNLS EIQG EVLS FDGN RTDK NYIR LEEL LTKQ LLAL DAVD PQGE EKCK AARK QAVR LAQN ILSY LDLK SDEW EY
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:BAG-5; CMD2F; BAG5
Positive Sample:SH-SY5Y,MCF7,Mouse lung,Mouse testis,Rat brain,Rat lung
Conjugate:Unconjugated
Cellular Localization:cytosol, mitochondrion, nucleus, perinuclear region of cytoplasm
Calculated MW:51kDa
Observed MW:51kDa

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:9529
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using BAG5 Rabbit pAb (CAB5794) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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