The Bag1 Polyclonal Antibody (CAB1104) is a valuable tool for researchers studying the Bag1 protein, which plays a crucial role in cell survival and apoptosis. This antibody, derived from rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the Bag1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies related to cell biology, cancer research, and apoptosis mechanisms.
Bag1, also known as Bcl-2-associated athanogene 1, is involved in multiple cellular processes, including protein folding, stress response, and apoptosis regulation. Dysregulation of Bag1 has been implicated in various diseases, making it a promising target for therapeutic interventions. By better understanding the functions and mechanisms of Bag1, researchers can potentially uncover new insights into disease pathogenesis and develop innovative treatment strategies.
Product Name:
BAG1 Rabbit Polyclonal Antibody
SKU:
CAB1104
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human BAG1 (NP_001165886.1).
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Purification Method:
Affinity purification
Gene ID:
573
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BAG1 antibody (CAB1104) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
