Bad Polyclonal Antibody (CAB16772)
- SKU:
- CAB16772
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Bad Polyclonal Antibody |
SKU: | CAB16772 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Bad (NP_004313.1). |
Sequence: | HQQE QPTS SSHH GGAG AVEI RSRH SSYP AGTE DDEG MGEE PSPF RGRS RSAP PNLW AAQR YGRE LRRM SDEF VDSF KKGL PRPK SAGT ATQM RQSS SWTR V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | BBC2; BCL2L8; Bad |
Positive Sample: | Mouse ovary |
Cellular Localization: | Cytoplasm, Mitochondrion outer membrane. |
Calculated MW: | 18kDa |
Observed MW: | 23kDa |
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Purification Method: | Affinity purification |
Gene ID: | 572 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |