The Bad Rabbit Monoclonal Antibody (CAB19595) is a unique tool for researchers studying the Bad Rabbit protein, a key factor in immune regulation and response. This monoclonal antibody, created through cutting-edge technology, specifically targets and binds to the Bad Rabbit protein in various cell types. The Bad Rabbit protein, also known as a regulator of immune response, plays a crucial role in modulating immune reactions and inflammation. Research shows that dysregulation of Bad Rabbit can lead to various immune-related disorders, making it a promising target for therapeutic interventions in diseases such as cancer, autoimmune conditions, and chronic inflammatory disorders.
Validated for use in Western blot applications, this antibody offers high specificity and sensitivity when detecting the Bad Rabbit protein in human samples. Its versatility and reliability make it an essential tool for immunology and cancer research studies aiming to better understand the mechanisms behind immune system regulation. By utilizing the Bad Rabbit Monoclonal Antibody (CAB19595), researchers can deepen their knowledge of immune response modulation and potentially pave the way for novel therapeutic approaches in immune-mediated diseases.
Product Name:
Bad Rabbit Monoclonal Antibody
SKU:
CAB19595
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bad (Q92934).
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Purification Method:
Affinity purification
Gene ID:
572
Clone Number:
ARC0074
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Bad Rabbit mAb (CAB19595) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
