Bad Rabbit Monoclonal Antibody (CAB19595)
- SKU:
- CAB19595
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Bad Rabbit Monoclonal Antibody |
SKU: | CAB19595 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bad (Q92934). |
Sequence: | MFQI PEFE PSEQ EDSS SAER GLGP SPAG DGPS GSGK HHRQ APGL LWDA SHQQ EQPT SSSH HGGA GAVE IRSR HSSY PAGT EDDE GMGE EPSP FRGR SRSA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | BBC2; BCL2L8; Bad |
Positive Sample: | HeLa,A549,Mouse brain,Mouse thymus,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion outer membrane. |
Calculated MW: | 18kDa |
Observed MW: | 20kDa |
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Purification Method: | Affinity purification |
Gene ID: | 572 |
Clone Number: | ARC0074 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |