BACE2 Rabbit Polyclonal Antibody (CAB14864)
- SKU:
- CAB14864
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BACE2 Rabbit Polyclonal Antibody |
SKU: | CAB14864 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-470 of human BACE2 (NP_036237.2). |
Sequence: | AGSG TNGG SLVL GGIE PSLY KGDI WYTP IKEE WYYQ IEIL KLEI GGQS LNLD CREY NADK AIVD SGTT LLRL PQKV FDAV VEAV ARAS LIPE FSDG FWTG SQLA CWTN SETP WSYF PKIS IYLR DENS SRSF RITI LPQL YIQP MMGA GLNY ECYR FGIS PSTN ALVI GATV MEGF YVIF DRAQ KRVG FAAS PCAE IAGA AVSE ISGP FSTE DVAS NCVP AQSL SEPI LWI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; BACE2 |
Positive Sample: | DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell surface, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Single-pass type I membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 25825 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |