BACE1 Rabbit Monoclonal Antibody (CAB11533)
- SKU:
- CAB11533
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | BACE1 Rabbit Monoclonal Antibody |
SKU: | CAB11533 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 402-501 of human BACE1 (P56817). |
Sequence: | FYVV FDRA RKRI GFAV SACH VHDE FRTA AVEG PFVT LDME DCGY NIPQ TDES TLMT IAYV MAAI CALF MLPL CLMV CQWR CLRC LRQQ HDDF ADDI SLLK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ASP2; BACE; HSPC104; BACE1 |
Positive Sample: | SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell surface, Cytoplasmic vesicle membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Single-pass type I membrane protein, trans-Golgi network. |
Calculated MW: | 56kDa |
Observed MW: | 70kDa |
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.
Purification Method: | Affinity purification |
Gene ID: | 23621 |
Clone Number: | ARC0696 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |