B4GALT4 Rabbit Polyclonal Antibody (CAB17029)
- SKU:
- CAB17029
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | B4GALT4 Rabbit Polyclonal Antibody |
SKU: | CAB17029 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-344 of human B4GALT4 (NP_003769.1). |
Sequence: | VGAI QEIP KAKE FMAN FHKT LILG KGKT LTNE ASTK KVEL DNCP SVSP YLRG QSKL IFKP DLTL EEVQ AENP KVSR GRYR PQEC KALQ RVAI LVPH RNRE KHLM YLLE HLHP FLQR QQLD YGIY VIHQ AEGK KFNR AKLL NVGY LEAL KEEN WDCF IFHD VDLV PEND FNLY KCEE HPKH LVVG RNST GYRL RYSG YFGG VTAL SREQ FFKV NGFS NNYW GWGG EDDD LRLR VELQ RMKI SRPL PEVG KYTM VFHT RDKG NEVN AERM KLLH QVSR VWRT DGLS SCSY KLVS VEHN PLYI NITV DFWF GA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | B4Gal-T4; beta4Gal-T4; B4GALT4 |
Positive Sample: | Mouse kidney,Rat thymus |
Cellular Localization: | Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8702 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |