B4GALT2 Rabbit Polyclonal Antibody (CAB17573)
- SKU:
- CAB17573
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | B4GALT2 Rabbit Polyclonal Antibody |
SKU: | CAB17573 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-271 of human B4GALT2 (NP_085076.2). |
Sequence: | PGVL MGGR YTPP DCTP AQTV AVII PFRH REHH LRYW LHYL HPIL RRQR LRYG VYVI NQHG EDTF NRAK LLNV GFLE ALKE DAAY DCFI FSDV DLVP MDDR NLYR CGDQ PRHF AIAM D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | B4Gal-T2; B4Gal-T3; beta4Gal-T2; B4GALT2 |
Positive Sample: | U-87MG,PC-3,OVCAR3,HT-29,Mouse brain,Mouse skeletal muscle,Mouse large intestine,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, nucleoplasm |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8704 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |