The B3GNT6 Polyclonal Antibody (CAB14975) is a valuable tool for researchers studying B3GNT6, an enzyme involved in glycosylation processes. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By binding specifically to the B3GNT6 protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential reagent for investigations in glycobiology and cancer research.B3GNT6 is a key player in glycosylation pathways, impacting cell signaling, cell adhesion, and protein function. Dysregulation of glycosylation processes, including alterations in B3GNT6 expression, have been implicated in cancer progression and metastasis.
Therefore, understanding the role of B3GNT6 through the use of this antibody can provide valuable insights into potential therapeutic targets for cancer treatment and diagnosis.Overall, the B3GNT6 Polyclonal Antibody is a reliable tool for researchers seeking to elucidate the functions of B3GNT6 in cellular processes and disease mechanisms. Its specificity and sensitivity make it a valuable asset for studies aiming to uncover the roles of glycosylation in health and disease.
Product Name:
B3GNT6 Rabbit Polyclonal Antibody
SKU:
CAB14975
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human B3GNT6 (NP_619651.3).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
43kDa
Observed MW:
43kDa
The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins.
Purification Method:
Affinity purification
Gene ID:
192134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat stomach, using B3GNT6 Rabbit pAb (CAB14975) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
