The B3GNT2 Polyclonal Antibody (CAB18418) is a valuable tool for researchers studying B3GNT2, a glycosyltransferase enzyme involved in the biosynthesis of glycoproteins and glycolipids. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the B3GNT2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential asset for studies in glycobiology and cancer research.B3GNT2 plays a crucial role in glycosylation processes, impacting cell adhesion, signaling, and immune responses.
Dysregulation of B3GNT2 has been linked to various diseases, including cancer and developmental disorders. Investigating the function of B3GNT2 using this antibody is essential for uncovering potential therapeutic targets for these conditions. By understanding the role of B3GNT2 in glycosylation pathways, researchers can develop targeted treatments that modulate glycan structures and cellular functions.
Product Name:
B3GNT2 Rabbit Polyclonal Antibody
SKU:
CAB18418
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-240 of human B3GNT2 (NP_006568.2).
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10678
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using B3GNT2 Rabbit pAb (CAB18418) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
