B3GALT4 Rabbit Polyclonal Antibody (CAB15341)
- SKU:
- CAB15341
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | B3GALT4 Rabbit Polyclonal Antibody |
SKU: | CAB15341 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-270 of human B3GALT4 (NP_003773.1). |
Sequence: | APEN LNQR NAIR ASWG GLRE ARGL RVQT LFLL GEPN AQHP VWGS QGSD LASE SAAQ GDIL QAAF QDSY RNLT LKTL SGLN WAEK HCPM ARYV LKTD DDVY VNVP ELVS ELVL RGGR WGQW ERST EPQR EAEQ EGGQ VLHS EEVP LLYL GRVH WRVN PSRT PGGR HRVS EEQW PHTW GPFP PYAS GTGY VLS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | GALT2; GALT4; BETA3GALT4; B3GALT4 |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Single-pass type II membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis.
Purification Method: | Affinity purification |
Gene ID: | 8705 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |