UniProt Protein Function: | B3GALNT2: Beta-1,3-N-acetylgalactosaminyltransferase active in synthesizing a unique carbohydrate structure, GalNAc-beta-1- 3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Belongs to the glycosyltransferase 31 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.4.1.-; Membrane protein, integral; TransferaseChromosomal Location of Human Ortholog: 1q42.3Cellular Component: Golgi membrane; endoplasmic reticulum; integral to membraneMolecular Function: acetylglucosaminyltransferase activity; acetylgalactosaminyltransferase activity; galactosyltransferase activityBiological Process: protein amino acid O-linked glycosylation; protein amino acid glycosylationDisease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 11 |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the glycosyltransferase 31 family. The encoded protein synthesizes GalNAc:beta-1,3GlcNAc, a novel carbohydrate structure, on N- and O-glycans. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2013] |
UniProt Code: | Q8NCR0 |
NCBI GenInfo Identifier: | 74751196 |
NCBI Gene ID: | 148789 |
NCBI Accession: | Q8NCR0.1 |
UniProt Secondary Accession: | Q8NCR0 |
UniProt Related Accession: | Q8NCR0 |
Molecular Weight: | 57kDa |
NCBI Full Name: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 |
NCBI Synonym Full Names: | beta-1,3-N-acetylgalactosaminyltransferase 2 |
NCBI Official Symbol: | B3GALNT2Â Â |
NCBI Official Synonym Symbols: | MDDGA11; B3GalNAc-T2Â Â |
NCBI Protein Information: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 |
UniProt Protein Name: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 |
UniProt Synonym Protein Names: | Beta-1,3-N-acetylgalactosaminyltransferase II |
Protein Family: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase |
UniProt Gene Name: | B3GALNT2Â Â |
UniProt Entry Name: | B3GL2_HUMAN |