Anti-B3GALNT1 Antibody (CAB7755)
- SKU:
- CAB7755
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-B3GALNT1 Antibody |
Antibody SKU: | CAB7755 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-331 of human B3GALNT1 (NP_003772.1). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | SKOV3, U-251MG |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-331 of human B3GALNT1 (NP_003772.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | IERV NWMY FYEY EPIY RQDF HFTL REHS NCSH QNPF LVIL VTSH PSDV KARQ AIRV TWGE KKSW WGYE VLTF FLLG QEAE KEDK MLAL SLED EHLL YGDI IRQD FLDT YNNL TLKT IMAF RWVT EFCP NAKY VMKT DTDV FINT GNLV KYLL NLNH SEKF FTGY PLID NYSY RGFY QKTH ISYQ EYPF KVFP PYCS GLGY IMSR DLVP RIYE MMGH VKPI KFED VYVG ICLN LLKV NIHI PEDT NLFF LYRI HLDV CQLR RVIA AHGF SSKE IITF WQVM LRNT TCHY |
Gene ID: | 8706 |
Uniprot: | O75752 |
Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
Calculated MW: | 39kDa |
Observed MW: | 45kDa |
Synonyms: | B3GALNT1, B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3 |
Background: | This gene is a member of the beta-1, 3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. |
UniProt Code: | O75752 |
NCBI GenInfo Identifier: | 84452146 |
NCBI Gene ID: | 8706 |
NCBI Accession: | NP_001033717.1 |
UniProt Secondary Accession: | O75752,Q920V1, Q6AY39, |
UniProt Related Accession: | O75752 |
Molecular Weight: | 39,512 Da |
NCBI Full Name: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 |
NCBI Synonym Full Names: | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
NCBI Official Symbol: | B3GALNT1Â Â |
NCBI Official Synonym Symbols: | P; P1; GLOB; GLCT3; galT3; Gb4Cer; B3GALT3; beta3Gal-T3Â Â |
NCBI Protein Information: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; b3Gal-T3; brainiac1; beta3GalT3; beta-3-Gx-T3; P antigen synthase; beta-1,3-GalNAc-T1; beta-1,3-GalTase 3; globoside synthase; P blood group globoside; beta-1,3-galactosyltransferase 3; globotriaosy |
UniProt Protein Name: | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 |
UniProt Synonym Protein Names: | Beta-1,3-galactosyltransferase 3; Beta-1,3-GalTase 3; Beta3Gal-T3; Beta3GalT3; b3Gal-T3; Beta-3-Gx-T3; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; Globoside synthase; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase |
Protein Family: | Probable beta-1,3-galactosyltransferase |
UniProt Gene Name: | B3GALNT1Â Â |
UniProt Entry Name: | B3GL1_HUMAN |